Form: 10KSB

Optional form for annual and transition reports of small business issuers [Section 13 or 15(d), not S-B Item 405]

June 29, 2006

Published on June 29, 2006

Exhibit 99.1

June 28, 2006
Mr. Jim Joyce
Aethlon Medical, Inc.
7825 Fay Avenue, Suite 200
La Jolla, CA 92037
Via Facsimile (858) 332-1739

Re: Board Resignation

Dear Mr. Joyce,

Please accept this letter as my formal notice to resign from the Board of
Aethlon Medical, Inc. The resignation is to be effective today.

Due to my missionary activities and other interests I have decided to relinquish
my responsibilities as a Board Member in order to devote more time and energy to
those missionary outreach programs.

It has been a great honor and privilege for me to work with you and the other
distinguished members of the Board over the past several years. I trust under
your leadership and the effort of the other Board Members and Able staff, you
will be able to take the Company to a much higher level of achievement in the
very near Future.

May God bless you all.

Warmest Regards,

/s/ Calvin M. Leung

Calvin M. Leung