EXHIBIT 31.1


CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350, AS ADOPTED
PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, James Joyce, certify that:

1. I have reviewed this Quarterly Report on Form 10-Q of Aethlon Medical,
Inc.;

2. Based on my knowledge, this Quarterly Report does not contain any
untrue statement of a material fact or omit to state a material fact
necessary to make the statements made, in light of the circumstances
under which such statements were made, not misleading with respect to
the period covered by this Report;

3. Based on my knowledge, the financial statements, and other financial
information included in this Report, fairly present in all material
respects the financial condition, results of operations and cash flows
of the smaller reporting company as of, and for, the periods presented
in this report;

4. The smaller reporting company's other certifying officer(s) and I are
responsible for establishing and maintaining disclosure controls and
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e))
and internal control over financial reporting (as defined in Exchange
Act Rules 13a-15(f) and 15d-15(f)) for the smaller reporting company
and have:

(a) Designed such disclosure controls and procedures, or caused
such disclosure controls and procedures to be designed under
our supervision, to ensure that material information relating
to the smaller reporting company, including its consolidated
subsidiaries, is made known to us by others within those
entities, particularly during the period in which this Report
is being prepared;

(b) Designed such internal control over financial reporting, or
caused such internal control over financial reporting to be
designed under our supervision, to provide reasonable
assurance regarding the reliability of financial reporting and
the preparation of financial statements for external purposes
in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the smaller reporting company's
disclosure controls and procedures and presented in this
Report and our conclusions about the effectiveness of the
disclosure controls and procedures, as of the end of the
period covered by this Report based on such evaluation; and


(d) Disclosed in this Report any change in the smaller reporting
company's internal control over financial reporting that
occurred during the smaller reporting company's most recent
fiscal quarter (the smaller reporting company's fourth fiscal
quarter in the case of an annual report) that has materially
affected, or is reasonably likely to materially affect, the
smaller reporting company's internal control over financial
reporting; and

5. The smaller reporting company's other certifying officer(s) and I have
disclosed, based on our most recent evaluation of internal control over
financial reporting, to the smaller reporting company's auditors and
the audit committee of the smaller reporting company's board of
directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the
design or operation of internal control over financial
reporting which are reasonably likely to adversely affect the
smaller reporting company's ability to record, process,
summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management
or other employees who have a significant role in the smaller
reporting company's internal control over financial reporting.

Date: August 14, 2009

/S/ JAMES A. JOYCE
-----------------------------
JAMES A. JOYCE
CHIEF EXECUTIVE OFFICER AND
CHIEF ACCOUNTING OFFICER
(PRINCIPAL EXECUTIVE OFFICER AND
PRINCIPAL ACCOUNTING OFFICER)